Statin drugs like Lipitor, Crestor, Pravachol and Zocor versus healthy policosanol alternative
You may have never heard of policosanol for combating cholesterol levels but the makers of Crestor, Zocor and Lipitor know very well about this natural alternative to high cholesterol levels.
What are Zocor, Crestor and Lipitor really, other than brand names for Simvastatin, Pravastatin and Atorvastatin. Granted, cholesterol levels, specifically LDL cholesterol levels have become more and more of a concern the last few decades in parts of the civilized world and diet has a lot to do with such elevated cholesterol levels. Now to find out about the safe alternative to statin drugs like Pravachol, Crestor, Lipitor and Zocor (Pravastatin, Rosuvastatin, Atorvastatin and Simvastatin), policosanol and its relevance to cholesterol levels and overall heart disease prevention.
The results from the policosanol research studies clearly demonstrate that policosanol is overall the absolute best answer to high cholesterol levels whether we are talking about a nutritional supplement, herbal product, or pharmaceutical drug and for the best form of bioavailability, pills, tablets and capsules offer inferior bioavailability when compared to suspended gel.
Policosanol is a mixture of fatty alcohols derived from the wax of sugarcane .(Saccharum officinarum, L.) These active substances work to lower cholesterol levels by several mechanisms including blocking the formation of cholesterol in the liver. The components of policosanol include 1-octacosanol, 1-dotriacontanol, 1-triacontanol, 1- tetracosanol, 1-tetratriacontanol, 1-hexacosanol, 1-heptacosanol and 1-nonacosanol. The Policosanol Research confirms that policosanol is indicated as an adjunct to dietary and lifestyle recommendations to reduce elevated LDL-C and total cholesterol levels. Its primarily application is in type II hypercholesterolemia including IIa subtype (characterized by elevated total serum cholesterol and LDL-C levels) and IIb subtype (mixed hypercholesterolemia characterized by elevated total serum cholesterol, LDL-C and triglyceride levels). Policosanol can also be used as an alternative to aspirin as an anti-platelet agent.
The recommended starting dose is 10-20 mg once a day with the evening meal, since cholesterol biosynthesis is increased at night and policosanol is much more effective when delivered in a gel because of its ability to be broken down and absorbed by the gastrointestinal tract and digestive system at a significantly higher rate than that of pills, tablets and capsules. From a pharmacological perspective and such studies, policosanol produces a dose-dependent and significant reduction of serum total cholesterol and LDL-C levels. HDL-C values were also increased in a dose-dependent manner. Triglycerides are also significantly reduced, but the reduction is not dose-dependent. Studies futher show that policosanol inhibits cholesterol synthesis at a point between the formation of acetate and mevalonate and that is extremely important and does not inhibit the natural production of CoQ10 (or coenzyme Q10) – cellular energy for muscles, including the critical heart muscle. Futhermore, policosanol not only effectively decreases serum cholesterol levels, but also reduces the cholesterol content in different tissues such as liver, heart and fatty tissue whereas statin drugs can cause significant liver damage and weaken the heart. Equally noteworthy and important is that the cholesterol-lowering effects of policosanol are persistent and it does not lose its effect over time. Summing up the pharmacological effects of policosanol, policosanol prevents and reverses atherosclerotic lesions and thrombosis, policosanol prevents intimal thickening and smooth muscle cell proferation, and policosanol is a highly effective antioxidant in preventing LDL oxidation.
Policosanol is an agent to lower cholesterol with exceptional clinical documentation demonstrating efficacy, safety and tolerability in patients with type II hypercholesterolemia and in patients with secondary hypercholesterolemia associated to diabetes mellitus or nephrotic syndrome. Futhermore, ingesting policosanol in a suspended gel enables superior bioavailability to other delivery forms such as pills, tablets and capsules. The policosanol research includes short and long-term, randomized, placebo-controlled and comparative studies versus statins (lovastatin, pravastatin and simvastatin), fibrates (bezafibrate and gemfibrozil), acipimox, and probucol involving nearly 3,000 subjects. If you’re currently taking statin drugs like Lipitor, Crestor, Zocor, Pravachol and others or are thinking about taking your doctor’s advice, you might quickly change your mind and start ingesting policosanol in a suspended gel named HRT.
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